This question has a couple of aspects. Variety is the spice of life and I like many variations of handguns from SA revolvers to semi-autos. I also appreciate being able to master the idiosyncrasies of each type. However, in a defensive situation, I try to remain constant with one gun. The reason is that at 0 dark 30, when the pucker factor is high, your adrenaline is pumping and your motors skills become questionable you will fall back on your training. You need the same gun to operate the same way without having to think about it. Because, you won't be able to think about it. You will be sub-consciously rehearsing how you have been trained. It's easy to believe that you will be able to have rational thought during a crisis, but the odds are you won't. No time to think, does this gun have a manual safety? Is this grip angle different? Where's the magazine latch? This is why, years ago, police officers killed in firefights were found with spent casings from their revolvers in their pockets. They had repeated this activity at the range over and over again. When it hit the fan, they did the same thing, capture the brass, put it in the pocket. No capacity for higher level thinking. The first time in training where I was pushed to this level of stress, I thought WTF! Why doesn't my hand work? This was full on contact, no protective gear except a FIST helmet and we were rolling on the ground trying to hurt each other. Some won't want to believe me. Just telling it like it is.
That said, whenever I decide to temporarily carry something different, I spend time with dry fire practice to ingrain in my brain that I'm carrying something different.
