My wife had a Gun Toten Mama's purse but thought it was too big. So when we went purse shopping she found one that was smaller but had a separate compartment for the pistol. Then I made her a holster to keep it oriented in the pocket for access. FWIW, the Gun Toten Mama's purse was nice and well built. She just does not like a large purse.
I've made a couple of kydex holsters with an ulticlip for women who wanted to CCW in a standard purse pocket. The Ulticlip will grab literally any fabric and hold the holster in place.