since there is a paywall, here is a long quote from :
Nitazenes belong to a class of synthetic opioids called isotonitazenes, or ISOs.
These compounds have gained attention due to their powerful painkilling properties.
First developed in the 1950s, nitazenes were never approved for medical use
and long remained obscure, known only in academic circles.
A defining trait of nitazenes is their extremely high potency—
hundreds to thousands of times more potent than morphine and other older opioids
and 10 to 20 times more powerful than fentanyl, which is already fueling the nation’s current drug crisis.
Although it’s theorized that these compounds are coming from China, “nobody really knows for sure,”
Dr. Jarid Pachter from Stony Brook Medicine, who specializes in family medicine and addiction medicine, told The Epoch Times.
So far, 20 distinct types of nitazenes have been detected in illegal street drugs, turning up with increasing frequency.
As Schedule I drugs in the United States, a class that includes drugs with no accepted medical use and high abuse and addiction potential, all nitazenes are illegal.
Nitazenes are being used to spike and strengthen illegal drugs while also making them cheaper to produce,
according to the U.S. Drug Enforcement Administration (DEA). But this chemical tampering has already led to deadly overdoses.
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Nitazenes belong to a class of synthetic opioids called isotonitazenes, or ISOs.
These compounds have gained attention due to their powerful painkilling properties.
First developed in the 1950s, nitazenes were never approved for medical use
and long remained obscure, known only in academic circles.
A defining trait of nitazenes is their extremely high potency—
hundreds to thousands of times more potent than morphine and other older opioids
and 10 to 20 times more powerful than fentanyl, which is already fueling the nation’s current drug crisis.
Although it’s theorized that these compounds are coming from China, “nobody really knows for sure,”
Dr. Jarid Pachter from Stony Brook Medicine, who specializes in family medicine and addiction medicine, told The Epoch Times.
So far, 20 distinct types of nitazenes have been detected in illegal street drugs, turning up with increasing frequency.
As Schedule I drugs in the United States, a class that includes drugs with no accepted medical use and high abuse and addiction potential, all nitazenes are illegal.
Nitazenes are being used to spike and strengthen illegal drugs while also making them cheaper to produce,
according to the U.S. Drug Enforcement Administration (DEA). But this chemical tampering has already led to deadly overdoses.