Much Stronger Than Fentanyl, Nitazene....report

turkeydance

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since there is a paywall, here is a long quote from :

Nitazenes belong to a class of synthetic opioids called isotonitazenes, or ISOs.
These compounds have gained attention due to their powerful painkilling properties.
First developed in the 1950s, nitazenes were never approved for medical use
and long remained obscure, known only in academic circles.


A defining trait of nitazenes is their extremely high potency—
hundreds to thousands of times more potent than morphine and other older opioids
and 10 to 20 times more powerful than fentanyl, which is already fueling the nation’s current drug crisis.

Although it’s theorized that these compounds are coming from China, “nobody really knows for sure,”
Dr. Jarid Pachter from Stony Brook Medicine, who specializes in family medicine and addiction medicine, told The Epoch Times.

So far, 20 distinct types of nitazenes have been detected in illegal street drugs, turning up with increasing frequency.
As Schedule I drugs in the United States, a class that includes drugs with no accepted medical use and high abuse and addiction potential, all nitazenes are illegal.

Nitazenes are being used to spike and strengthen illegal drugs while also making them cheaper to produce,
according to the U.S. Drug Enforcement Administration (DEA). But this chemical tampering has already led to deadly overdoses.
 
So far, 20 distinct types of nitazenes have been detected in illegal street drugs, turning up with increasing frequency.
This is what happens when you push bad policy in the name of fighting the “opioid crisis”. People suffer in pain and the quacks won’t prescribe out of fear and people will turn to alternate methods to get relief. How do I know? Because I’ve been there.
 
regarding: "...the 'good' news is narcan works on them..."
from the report:
Most patients overdosing on nitazenes or other novel opioids need two or more naloxone doses,
whereas fentanyl overdoses require just one, according to research published in JAMA Network Open.
 
regarding: "...the 'good' news is narcan works on them..."
from the report:
Most patients overdosing on nitazenes or other novel opioids need two or more naloxone doses,
whereas fentanyl overdoses require just one, according to research published in JAMA Network Open.

Almost no opioid overdose--real overdose, not just an extra dose--requires a couple or more narcan pushes followed by a narcan drip. Half live of narcan is, on average, about 40 minutes. The half life of nitazene is pretty long, so you need multiple push does and likely a drip. Half life of fent is 3 /1/2, 4 hours; morphine is 3 hours; dilaudid is 2 hours; ocycodone and similar is about 3 hours.

Interesting what JAMA said; I have never, ever needed just one dose of narcan on any opioid OD, regardless of the source.
 
I do wish that we’d stop pretending that the opioide crisis isna result of gram leaving half a bottle of pain killers in her medicine cabinet. Can’t fix the problem until we admit the problem.

FWIW, found out last week that an acquaintance of mine is a fentanyl addict. Habit was close to $5k per week. Got back from rehab a couple weeks ago and is already stealing vodka from the restaurant and smoking a little weed. She’s hanging out with the same old group. It’s a pity.
 
Put pallets of the stuff on several street corners in major cities and let Darwin sort it all out, the prices will crash and certain crime rates will drop due to availability.

The down side is that the cartels will not sit back and lose that cash cow so they’ll move to some other type of crime though.
 
China throwing fuel on another fire that's burning this country down.
Chinese took a lesson from the Brits when Britain paid for the imported tea with exports (through India) of opium to China.
 
I was given fentanyl in the ER Friday night, a "trauma dose" - a whopping 50 micro grams.

Not exactly exactly what I'd call a party drug.

And that dose was way too low for what they were doing.
 
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