I want to throw my 2c as I shot Taurus TX22 today, Browning Buckmark last weekend, and Ruger Mark IV several weeks back. All of them are great guns.
The Buckmark and the Mark IV had much better groups, but the TX22 is not that bad either.
All three of them failed miserably with one brand of problematic ammo. All worked well very with everything else.
The huge advantage of the TX22 is the magazine capacity - 16 rounds. Then there are extensions. 19 to 21 rounds (loading does not always work to the max) is very fun.
There are extensions for the Marks, but far even from the stock 16 rounds of the TX22.
For aftermarket support, the Mark's are the kings - anything you may want is done by someone.
The aftermarket support is most limited for the Buckmark.
For the TX22 there are some good upgrades, but I expect more to come.
Ergonomics very much depends on the hands of the shooter.
For me, even I liked the TX22 most, the very strongly pronounced hump was annoying.
There are a lot of strong opinions for the regular Marks vs. the 22/45s. I find them both fitting *my* hand very well.
The TX22 is a very lightweight gun - polymer frame, aluminum slide.
The Buckmarks and the Marks have endless variants, some lighter some heavier. To be honest I do not know the variants. I shot the gun in front of me, and I enjoyed it. Someone more knowledgeable probably could write a Ph.D. thesis on the subject.
And then someone suggested airsoft guns.
In other times one could dismiss that as some joke that missed the spot.
Today... Well, to be honest, I am seriously considering that option.
Thanks and kudo to
@wvsig for the suggestion, as I know nothing in the airsoft world.