C-More red dots are the crispiest for me and my astigmatism. The Romeo Max Michel thing, whatever it is called, is expensive as crap but is also pretty nice.
But the best is going to be a prism sight hands down. If it is viable for your platform that's what I would go with. I can't always do that with every rifle or pistol for obvious reasons, but some of my optics are about to migrate to prism sights for this very reason.
Just wish they made a prism scope that was lightweight, 1X, and only has a simple dot instead of concentric circles or some sort of horseshoe.