I'll second the Remington Solid Copper Sabots. The Solid in the name is a bit oxymoronic as it has four petals that break off the main projectile creating five wound channels. The last time I used one, the buck dropped so hard that I thought I had caught him in the spine. The field dressing showed no spine hit, just a clean upper lung shot.
After numerous times seeing deer turn on the afterburners for a quarter mile death sprint after loosing a significant chunk of their heart, I was pleased to not have to track it down. If I'm in a shotgun only zone, that will be the load I use.
Edit to add that I shoot an 870 but the barrel is a Hastings.